Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2396694 | 0.92 | JAK2 (0.55) | JAK2JAK1 | |
| SCHEMBL2398827 | 0.90 | JAK2 (0.55) | JAK2JAK1 | |
| SCHEMBL2396043 | 0.88 | JAK2 (0.52) | JAK2JAK1 | |
| SCHEMBL2393098 | 0.87 | JAK2 (0.53) | JAK2JAK1 | |
| SCHEMBL2399602 | 0.86 | JAK2 (0.55) | JAK2JAK1 | |
| SCHEMBL2392344 | 0.84 | JAK2 (0.51) | JAK2JAK1 | |
| SCHEMBL12263222 | 0.84 | JAK2 (0.46) | JAK2JAK1 | |
| SCHEMBL871972 | 0.84 | JAK2 (0.44) | JAK2JAK1 | |
| SCHEMBL18036541 | 0.83 | JAK2 (0.36) | JAK2JAK1 | |
| SCHEMBL20958245 | 0.83 | AXL (0.47) | JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545045-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | Incyte Corporation (US) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011112662-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | INCYTE CORPORATION (US) | 2011-09-15 | — | — | WO | disclosed |