Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 19/20 | 0.68 |
| ▸ | BCL2 | P10415 | 14/20 | 0.64 |
| ▸ | BCL2L2 | Q92843 | 6/20 | 0.64 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25422833 | 1.00 | BCL2L1 (0.68) | BCL2L1BCL2BCL2L2MCL1ALB | |
| SCHEMBL555323 | 0.97 | BCL2L1 (0.72) | BCL2L1BCL2BCL2L2MCL1ALB | |
| SCHEMBL555322 | 0.97 | BCL2L1 (0.72) | BCL2L1BCL2BCL2L2MCL1ALB | |
| SCHEMBL3819345 | 0.97 | BCL2L1 (0.72) | BCL2L1BCL2BCL2L2MCL1ALB | |
| SCHEMBL29482082 | 0.97 | BCL2L1 (0.72) | BCL2L1BCL2BCL2L2MCL1ALB | |
| SCHEMBL31570886 | 0.93 | BCL2L1 (0.70) | BCL2L1BCL2BCL2L2MCL1ALB | |
| SCHEMBL3819283 | 0.93 | BCL2L1 (0.70) | BCL2L1BCL2BCL2L2MCL1ALB | |
| SCHEMBL4747130 | 0.92 | BCL2L1 (0.69) | BCL2L1BCL2BCL2L2MCL1ALB | |
| SCHEMBL3823004 | 0.92 | BCL2L1 (0.69) | BCL2L1BCL2BCL2L2MCL1ALB | |
| SCHEMBL3822342 | 0.92 | BCL2L1 (0.69) | BCL2L1BCL2BCL2L2MCL1ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444717-A1 | BCL-XL/BCL-2 DUAL DEGRADERS FOR TREATMENT OF CANCERS | University of Florida Research Foundation, Incorporated (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107606-A1 | BCL-XL/BCL-2 DUAL DEGRADERS FOR TREATMENT OF CANCERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-06-15 | — | — | WO | disclosed |