Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.64 |
| ▸ | CA4 | P22748 | 3/20 | 0.56 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL29238921 | 0.97 | CA1 (0.60) | CA1CA4FAHD1MEN1KMT2A | |
| Acetic Acid SCHEMBL26982602 | 0.96 | CA1 (0.69) | CA1CA4FAHD1MEN1KMT2A | |
| Acetic Acid SCHEMBL27519987 | 0.94 | CA1 (0.56) | CA1CA4FAHD1MEN1KMT2A | |
| Acetic Acid SCHEMBL12465625 | 0.89 | CA1 (0.61) | CA1CA4MEN1KMT2ACA2 | |
| Acetic Acid SCHEMBL7593550 | 0.89 | CA1 (0.61) | CA1CA4MEN1KMT2ACA2 | |
| Acetic Acid SCHEMBL19432974 | 0.89 | — | — | |
| Acetic Acid SCHEMBL7517431 | 0.89 | — | — | |
| Acetic Acid SCHEMBL6403805 | 0.89 | CA1 (0.61) | CA1CA4MEN1KMT2ACA2 | |
| Acetic Acid SCHEMBL17312004 | 0.89 | CA1 (0.61) | CA1CA4MEN1KMT2ACA2 | |
| Acetic Acid SCHEMBL11660792 | 0.89 | CA1 (0.61) | CA1CA4MEN1KMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3698014-B1 | METHOD FOR FORMING HIGH EFFICIENCY GEOTHERMAL WELLBORES | EAVOR TECH INC (CA) | 2023-07-05 | — | — | EP | disclosed |