Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 3/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | PRKACA | P17612 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CLK2 | P49760 | 2/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.38 |
| ▸ | PRKX | P51817 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.38 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.38 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30509671 | 1.00 | HTR2A (0.41) | HTR2AHTR2CHTR2BHSD11B1JAK3 | |
| SCHEMBL25426220 | 0.86 | HTR2A (0.43) | HTR2AHTR2CHTR2BHSD11B1JAK3 | |
| SCHEMBL30548036 | 0.86 | HTR2A (0.43) | HTR2AHTR2CHTR2BHSD11B1JAK3 | |
| SCHEMBL25427220 | 0.85 | HTR2A (0.42) | HTR2AHTR2CHTR2BHSD11B1JAK3 | |
| SCHEMBL30509689 | 0.85 | HTR2A (0.42) | HTR2AHTR2CHTR2BHSD11B1JAK3 | |
| SCHEMBL25425318 | 0.84 | HTR2A (0.41) | HTR2AHTR2CHTR2BHSD11B1JAK3 | |
| SCHEMBL30509694 | 0.84 | HTR2A (0.41) | HTR2AHTR2CHTR2BHSD11B1JAK3 | |
| SCHEMBL30548009 | 0.81 | DTYMK (0.41) | HTR2AHTR2CHTR2BHSD11B1JAK3 | |
| SCHEMBL25422396 | 0.81 | DTYMK (0.41) | HTR2AHTR2CHTR2BHSD11B1JAK3 | |
| SCHEMBL1816384 | 0.81 | CHEK1 (0.48) | HTR2AHTR2CHTR2BJAK3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141225-A1 | FUSED HETEROCYCLES AS 5-HT2A RECEPTOR AGONISTS | ONSERO THERAPEUTICS INC. (US) | 2023-07-27 | — | — | WO | disclosed |
| WO-2023141225-A1 | FUSED HETEROCYCLES AS 5-HT2A RECEPTOR AGONISTS | ONSERO THERAPEUTICS INC. (US) | 2023-07-27 | — | — | WO | disclosed |