Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.60 |
| ▸ | IKZF2 | Q9UKS7 | 9/20 | 0.55 |
| ▸ | WIZ | O95785 | 1/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006961 | 0.92 | CRBN (0.64) | CRBN | |
| SCHEMBL27090510 | 0.92 | CRBN (0.64) | CRBN | |
| SCHEMBL22828005 | 0.85 | CRBN (0.65) | CRBNIKZF2WIZCSNK1A1 | |
| SCHEMBL17552859 | 0.84 | CRBN (0.69) | CRBNIKZF2WIZCSNK1A1 | |
| SCHEMBL24319331 | 0.84 | CRBN (0.69) | CRBNIKZF2WIZCSNK1A1 | |
| SCHEMBL25996067 | 0.82 | CRBN (0.69) | CRBNIKZF2WIZCSNK1A1 | |
| SCHEMBL25727623 | 0.81 | CRBN (0.62) | CRBNIKZF2WIZCSNK1A1 | |
| SCHEMBL30851278 | 0.81 | CRBN (0.69) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL22566723 | 0.81 | IKZF2 (0.65) | CRBNIKZF2WIZ | |
| SCHEMBL19503638 | 0.81 | CRBN (0.65) | CRBNIKZF2CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466260-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | Astrazeneca AB (SE) | 2024-11-27 | — | — | EP | disclosed |
| CN-118574821-A | Compounds and their use in the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2024-08-30 | — | — | CN | disclosed |
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |