Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.59 |
| ▸ | BRDT | Q58F21 | 10/20 | 0.53 |
| ▸ | BRD2 | P25440 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2544018 | 0.90 | BRD4 (0.71) | BRD4BRDTBRD2 | |
| SCHEMBL2538223 | 0.90 | BRD4 (0.71) | BRD4BRDTBRD2 | |
| SCHEMBL2545078 | 0.89 | BRD4 (0.70) | BRD4BRDT | |
| SCHEMBL2545084 | 0.89 | BRD4 (0.70) | BRD4BRDT | |
| SCHEMBL2545017 | 0.89 | BRD4 (0.63) | BRD4BRDTBRD2 | |
| SCHEMBL2539256 | 0.89 | BRD4 (0.63) | BRD4BRDTBRD2 | |
| SCHEMBL2539741 | 0.88 | BRD4 (0.55) | BRD4BRDT | |
| SCHEMBL2542061 | 0.87 | BRD4 (0.68) | BRD4BRDT | |
| SCHEMBL3204769 | 0.87 | BRD4 (0.71) | BRD4BRDTBRD2 | |
| SCHEMBL2542040 | 0.86 | BRD4 (0.63) | BRD4BRDTBRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044042-B2 | Thienotriazolodiazepine compound and medicinal use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-10-25 | — | — | US | disclosed |