Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30590308 | 1.00 | RAD51 (0.62) | RAD51KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL25431865 | 0.91 | RAD51 (0.55) | RAD51KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL30590309 | 0.91 | RAD51 (0.55) | RAD51KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL25433099 | 0.87 | RAD51 (0.63) | RAD51KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL30590352 | 0.87 | RAD51 (0.69) | RAD51KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL25432853 | 0.87 | RAD51 (0.69) | RAD51KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL26064317 | 0.86 | RAD51 (0.58) | RAD51KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL25430619 | 0.82 | RAD51 (0.80) | RAD51KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL25429800 | 0.82 | RAD51 (0.65) | RAD51KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL25432536 | 0.79 | RAD51 (0.55) | RAD51KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161782-A1 | NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS | SATYARX PHARMA INNOVATIONS PVT LTD (IN) | 2023-08-31 | — | — | WO | disclosed |
| WO-2023161782-A1 | NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS | SATYARX PHARMA INNOVATIONS PVT LTD (IN) | 2023-08-31 | — | — | WO | disclosed |