Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 12/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 4/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 4/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 4/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 1/20 | 1.00 |
| ▸ | SCN1A | P35498 | 4/20 | 0.81 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.81 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.81 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.74 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroquinine SCHEMBL109600 | 1.00 | CYP2D6 (1.00) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| Hydroquinidine SCHEMBL308963 | 1.00 | CYP2D6 (1.00) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| Hydroquinine SCHEMBL109601 | 1.00 | CYP2D6 (1.00) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| Hydroquinidine SCHEMBL22754573 | 1.00 | CYP2D6 (1.00) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| Hydroquinidine SCHEMBL109603 | 1.00 | CYP2D6 (1.00) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| Hydroquinidine SCHEMBL23509584 | 1.00 | CYP2D6 (1.00) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| Hydroquinidine SCHEMBL109602 | 1.00 | CYP2D6 (1.00) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| Hydroquinidine SCHEMBL25429352 | 1.00 | CYP2D6 (1.00) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| Hydroquinidine SCHEMBL22754576 | 1.00 | CYP2D6 (1.00) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| Hydroquinidine SCHEMBL308962 | 1.00 | CYP2D6 (1.00) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4465819-A1 | A METHOD OF PLANT TREATMENT WITH QUINOLINE ALKALOIDS AND PESTICIDE COMPOSITIONS THEREOF | Metabolic Insights Ltd. (IL) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023139574-A1 | A METHOD OF PLANT TREATMENT WITH QUINOLINE ALKALOIDS AND PESTICIDE COMPOSITIONS THEREOF | METABOLIC INSIGHTS LTD. (IL) | 2023-07-27 | — | — | WO | disclosed |