Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.45 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25339995 | 0.87 | FEN1 (0.45) | PDE10AFEN1ALDH1A1MAPTATM | |
| SCHEMBL25431453 | 0.86 | FEN1 (0.40) | PDE10AFEN1 | |
| SCHEMBL25340198 | 0.81 | TRPV1 (0.44) | PDE10AFEN1TRPV1 | |
| SCHEMBL25339531 | 0.81 | FEN1 (0.45) | PDE10AFEN1TRPV1 | |
| SCHEMBL25952851 | 0.80 | PDE10A (0.33) | PDE10AFEN1 | |
| SCHEMBL25338851 | 0.80 | TRPV1 (0.50) | PDE10AFEN1TRPV1 | |
| SCHEMBL25340087 | 0.80 | FEN1 (0.44) | PDE10AFEN1TRPV1 | |
| SCHEMBL25340070 | 0.76 | FEN1 (0.51) | PDE10AFEN1TRPV1 | |
| SCHEMBL25377363 | 0.76 | PDE10A (0.54) | PDE10AFEN1ALDH1A1MAPTATM | |
| SCHEMBL7010347 | 0.76 | S1PR1 (0.43) | PDE10AFEN1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |