Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30544072 | 1.00 | TRPV1 (0.46) | TRPV1EPHX2GRM4TOP1FLT1 | |
| SCHEMBL25340468 | 0.87 | TRPV1 (0.49) | TRPV1EPHX2GRM4 | |
| SCHEMBL25439475 | 0.85 | PIP4K2A (0.42) | GRM4 | |
| SCHEMBL25430912 | 0.84 | TRPV1 (0.47) | TRPV1EPHX2 | |
| SCHEMBL25428478 | 0.83 | TRPV1 (0.42) | TRPV1EPHX2GRM4KDR | |
| SCHEMBL30544141 | 0.79 | PDE10A (0.45) | TRPV1TOP1 | |
| SCHEMBL25427930 | 0.79 | PDE10A (0.45) | TRPV1TOP1 | |
| SCHEMBL25974136 | 0.75 | EPHX2 (0.48) | TRPV1EPHX2GRM4 | |
| SCHEMBL25974137 | 0.75 | TRPV1 (0.49) | TRPV1EPHX2 | |
| SCHEMBL30482552 | 0.75 | EGFR (0.47) | TRPV1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |