Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 17/20 | 0.55 |
| ▸ | CDK12 | Q9NYV4 | 17/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 16/20 | 0.55 |
| ▸ | CDK2 | P24941 | 16/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 14/20 | 0.55 |
| ▸ | CDK9 | P50750 | 14/20 | 0.55 |
| ▸ | CDK7 | P50613 | 10/20 | 0.55 |
| ▸ | CCNH | P51946 | 10/20 | 0.55 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31122417 | 1.00 | CCNK (0.55) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25433279 | 1.00 | CCNK (0.55) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL30457188 | 0.95 | CCNK (0.55) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25360949 | 0.95 | CCNK (0.55) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL30455901 | 0.93 | CCNK (0.54) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25362281 | 0.93 | CCNK (0.54) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL30456284 | 0.89 | CCNK (0.51) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25363347 | 0.89 | CCNK (0.51) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25363350 | 0.89 | CCNK (0.51) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25364596 | 0.88 | CCNK (0.55) | CCNKCDK12CCNE1CDK2CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116761-A1 | PYRIMIDINE HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 英矽智能科技知识产权有限公司 | 2023-06-29 | — | — | WO | disclosed |