SCHEMBL25435975

SCHEMBL25435975

COC(=O)NC(C(=O)N1CCC[C@]1(C(=O)O)C1CCC1)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25435979 1.00 NR1I2 (0.34) NR1I2
SCHEMBL6778071 0.76 KMT2A (0.38)
SCHEMBL6980673 0.70
SCHEMBL7378319 0.70 DPP4 (0.36)
Hydrochloric Acid SCHEMBL6338693 0.69 DPP4 (0.35)
SCHEMBL15457778 0.68 CNR2 (0.38) NR1I2
SCHEMBL8297153 0.68 CNR2 (0.38) NR1I2
SCHEMBL12335712 0.68 ACE (0.48)
SCHEMBL8604933 0.68 GRIN2B (0.30)
SCHEMBL5900915 0.67 MEN1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023133174-A1 PROTEASE INHIBITORS FOR TREATING OR PREVENTING CORONAVIRUS INFECTION MERCK SHARP & DOHME LLC (US) 2023-07-13 WO disclosed