Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | SNCA | P37840 | 16/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9935406 | 0.89 | HPGD (0.60) | HPGDSNCATRPV1 | |
| SCHEMBL25424689 | 0.89 | HPGD (0.59) | HPGDSNCAABCG2MTNR1AMTNR1B | |
| SCHEMBL15345910 | 0.86 | HPGD (0.58) | HPGDSNCA | |
| SCHEMBL9937673 | 0.83 | SNCA (0.70) | SNCA | |
| SCHEMBL9938785 | 0.80 | SNCA (0.69) | SNCA | |
| SCHEMBL9883644 | 0.79 | SNCA (0.52) | HPGDSNCAMTNR1AMTNR1B | |
| SCHEMBL9883529 | 0.77 | SNCA (0.51) | HPGDSNCAMTNR1AMTNR1B | |
| SCHEMBL15345946 | 0.75 | SNCA (0.59) | SNCAMTNR1AMTNR1BTRPV1 | |
| SCHEMBL9935560 | 0.75 | SNCA (0.83) | SNCATRPV1 | |
| SCHEMBL9883534 | 0.75 | SNCA (0.48) | HPGDSNCAABCG2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130070-A2 | CARBOLINE COMPOUNDS AND USE THEREOF | PTC THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |