Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8513298 | 1.00 | CHRM4 (0.34) | CHRM4ACACBNPC1RAB9AAKR1C3 | |
| SCHEMBL8513303 | 1.00 | CHRM4 (0.34) | CHRM4ACACBNPC1RAB9AAKR1C3 | |
| SCHEMBL8512856 | 0.89 | AKR1C3 (0.32) | CHRM4ACACBAKR1C3PDE10A | |
| SCHEMBL25435089 | 0.89 | AKR1C3 (0.32) | CHRM4ACACBAKR1C3PDE10A | |
| SCHEMBL8512859 | 0.89 | AKR1C3 (0.32) | CHRM4ACACBAKR1C3PDE10A | |
| SCHEMBL25437153 | 0.82 | ACACB (0.35) | CHRM4ACACBAKR1C3PDE10AHDAC3 | |
| SCHEMBL8510068 | 0.74 | PDE10A (0.42) | RAB9APDE10AHDAC3HDAC4HDAC1 | |
| SCHEMBL8510075 | 0.74 | PDE10A (0.42) | RAB9APDE10AHDAC3HDAC4HDAC1 | |
| SCHEMBL9994507 | 0.73 | CHRM4 (0.33) | CHRM4NPC1RAB9AAKR1C3LMNA | |
| SCHEMBL25435091 | 0.72 | ACACB (0.34) | CHRM4ACACBNPC1RAB9AAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856735-B1 | FUSED BICYCLIC HETEROCYCLES AS THERAPEUTIC AGENTS | UNIV NEW YORK (US) | 2023-09-06 | — | — | EP | claimed |