SCHEMBL25437334

SCHEMBL25437334

COc1ccc(-c2noc(N3CCN(C(=O)C4CCCNC4)CC3)n2)cc1

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.65
▸ TP53 P04637 4/20 0.65
▸ LMNA P02545 5/20 0.64
▸ HTT P42858 2/20 0.63
▸ SMN1; SMN2 Q16637 2/20 0.63
▸ THRB P10828 1/20 0.63
▸ KDM4E B2RXH2 1/20 0.63
▸ ALDH1A1 P00352 1/20 0.63
▸ HSD17B10 Q99714 1/20 0.63
▸ NPC1 O15118 1/20 0.61
▸ HSP90AA1 P07900 1/20 0.52
▸ MEN1 O00255 3/20 0.51
▸ KMT2A Q03164 3/20 0.51
▸ POLB P06746 1/20 0.51
▸ RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL25404149 0.99 MAPT (0.64) MAPTTP53LMNAHTTSMN1; SMN2
SCHEMBL31546398 0.83 MAPT (0.75) MAPTTP53LMNAHTTSMN1; SMN2
SCHEMBL31546324 0.81 MAPT (0.69) MAPTTP53LMNAHTTSMN1; SMN2
SCHEMBL31546316 0.79 MAPT (0.76) MAPTTP53LMNAHTTSMN1; SMN2
SCHEMBL25436034 0.79 MAPT (0.58) MAPTTP53LMNAHTTSMN1; SMN2
SCHEMBL30584755 0.79 MAPT (0.61) MAPTTP53LMNAHTTSMN1; SMN2
SCHEMBL25433381 0.79 MAPT (0.73) MAPTTP53LMNAHTTSMN1; SMN2
Hydrochloric Acid SCHEMBL30584907 0.79 MAPT (0.58) MAPTTP53LMNAHTTSMN1; SMN2
SCHEMBL31546366 0.79 MAPT (0.72) MAPTTP53LMNAHTTSMN1; SMN2
SCHEMBL30584774 0.78 MAPT (0.67) MAPTTP53LMNAHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MAPT 2999/4885TP53 54/4885LMNA 1344/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MAPT 2999/4885TP53 54/4885LMNA 1344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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