Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT7 | O95251 | 20/20 | 0.69 |
| ▸ | KAT6A | Q92794 | 20/20 | 0.69 |
| ▸ | KAT6B | Q8WYB5 | 17/20 | 0.69 |
| ▸ | KAT5 | Q92993 | 13/20 | 0.69 |
| ▸ | KAT8 | Q9H7Z6 | 13/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184731 | 1.00 | KAT7 (0.69) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL30801363 | 0.95 | KAT7 (0.64) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25045842 | 0.95 | KAT7 (0.64) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL31028384 | 0.95 | KAT7 (0.68) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25045967 | 0.95 | KAT7 (0.68) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25045838 | 0.95 | KAT7 (0.65) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL30801364 | 0.95 | KAT7 (0.65) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25562122 | 0.95 | KAT7 (0.67) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL31494530 | 0.92 | KAT7 (0.62) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25438399 | 0.92 | KAT7 (0.62) | KAT7KAT6AKAT6BKAT5KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4385989-A1 | SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2024-06-19 | — | — | EP | disclosed |
| CN-117597341-A | Sulfonamide derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-02-23 | — | — | CN | disclosed |
| WO-2023114710-A1 | FUSED BENZOISOXAZOLYL COMPOUNDS AS KAT6A INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023114710-A1 | FUSED BENZOISOXAZOLYL COMPOUNDS AS KAT6A INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023088233-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-25 | — | — | WO | disclosed |