Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 19/20 | 0.60 |
| ▸ | BRD2 | P25440 | 1/20 | 0.44 |
| ▸ | BRDT | Q58F21 | 6/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2536973 | 0.93 | BRD4 (0.51) | BRD4BRD2BRDTADORA3TSPO | |
| SCHEMBL2542066 | 0.92 | BRD4 (0.70) | BRD4BRD2BRDTADORA3TSPO | |
| SCHEMBL2538080 | 0.91 | BRD4 (0.55) | BRD4BRD2BRDTADORA3TSPO | |
| SCHEMBL2541824 | 0.90 | BRD4 (0.54) | BRD4BRD2BRDTADORA3TSPO | |
| SCHEMBL2541829 | 0.89 | BRD4 (0.54) | BRD4BRD2BRDTADORA3TSPO | |
| SCHEMBL2543487 | 0.88 | BRD4 (0.51) | BRD4BRDT | |
| SCHEMBL2540750 | 0.88 | BRD4 (0.58) | BRD4BRDT | |
| SCHEMBL3207165 | 0.86 | BRD4 (0.73) | BRD4BRD2BRDTADORA3TSPO | |
| SCHEMBL2541090 | 0.84 | BRD4 (0.57) | BRD4BRDTADORA3TSPO | |
| SCHEMBL2541095 | 0.84 | BRD4 (0.57) | BRD4BRDTADORA3TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044042-B2 | Thienotriazolodiazepine compound and medicinal use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-10-25 | — | — | US | disclosed |