Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.82 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.82 |
| ▸ | F2 | P00734 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Betrixaban SCHEMBL158591 | 0.90 | F10 (1.00) | F10KCNH2F2 | |
| Betrixaban SCHEMBL29374026 | 0.90 | F10 (1.00) | F10KCNH2F2 | |
| Betrixaban SCHEMBL29858125 | 0.89 | F10 (0.98) | F10KCNH2F2 | |
| Betrixaban SCHEMBL20587589 | 0.87 | F10 (0.90) | F10KCNH2F2 | |
| Betrixaban SCHEMBL20587587 | 0.87 | F10 (0.90) | F10KCNH2F2 | |
| SCHEMBL22136974 | 0.87 | F10 (0.83) | F10KCNH2F2 | |
| SCHEMBL2607614 | 0.85 | F10 (0.80) | F10KCNH2F2 | |
| SCHEMBL890921 | 0.85 | F10 (0.79) | F10KCNH2F2 | |
| SCHEMBL2438967 | 0.84 | F10 (0.79) | F10KCNH2F2 | |
| SCHEMBL765235 | 0.84 | F10 (0.85) | F10KCNH2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031017-A1 | CRYSTALLINE FORMS OF A FACTOR Xa INHIBITOR | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-03-08 | — | — | WO | disclosed |