SCHEMBL25449285

SCHEMBL25449285

c1ccc(-c2ccc([Si](c3ccccc3)(c3ccccc3)c3cccc(-c4nc(-n5c6ccccc6c6ccccc65)nc(-n5c6ccccc6c6ccccc65)n4)c3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ABCG2 Q9UNQ0 4/20 0.33
ABCB1 P08183 2/20 0.33
NR1I3 Q14994 3/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
VDR P11473 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2B6 P20813 1/20 0.32
AHR P35869 1/20 0.32
MEN1 O00255 2/20 0.31
LMNA P02545 2/20 0.31
KMT2A Q03164 2/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
USP2 O75604 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26426613 0.96 ABCG2 (0.34) KDM4EATML3MBTL1ABCG2ABCB1
SCHEMBL25449290 0.96 MEN1 (0.35) KDM4EATML3MBTL1ABCG2ABCB1
SCHEMBL25449486 0.96 MEN1 (0.35) KDM4EATML3MBTL1ABCG2ABCB1
SCHEMBL25449269 0.96 KDM4E (0.35) KDM4EATML3MBTL1ABCG2ABCB1
SCHEMBL25449265 0.96 KDM4E (0.35) KDM4EATML3MBTL1ABCG2ABCB1
SCHEMBL30846074 0.96 KDM4E (0.37) KDM4EATML3MBTL1ABCG2ABCB1
SCHEMBL22038577 0.96 KDM4E (0.37) KDM4EATML3MBTL1ABCG2ABCB1
SCHEMBL23622549 0.96 KDM4E (0.37) KDM4EATML3MBTL1ABCG2ABCB1
SCHEMBL25449275 0.95 MEN1 (0.34) KDM4EATML3MBTL1ABCG2ABCB1
SCHEMBL23065646 0.95 MEN1 (0.36) KDM4EATML3MBTL1ABCG2ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230141905-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-11 US disclosed
US-20230141905-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-11 US disclosed