Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.57 |
| ▸ | INSR | P06213 | 15/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.57 |
| ▸ | NPM1 | P06748 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25451006 | 0.96 | ALK (0.58) | ALKINSRKCNH2NPM1CYP3A4 | |
| SCHEMBL24179117 | 0.90 | ALK (0.59) | ALKINSRKCNH2NPM1 | |
| SCHEMBL24178914 | 0.89 | ALK (0.49) | ALKINSRKCNH2NPM1CYP3A4 | |
| SCHEMBL24179116 | 0.89 | EGFR (0.51) | ALKINSRKCNH2 | |
| SCHEMBL24178970 | 0.86 | ALK (0.58) | ALKINSRKCNH2NPM1CYP3A4 | |
| SCHEMBL24178969 | 0.83 | ALK (0.59) | ALKINSRKCNH2NPM1CYP3A4 | |
| SCHEMBL24178916 | 0.82 | EGFR (0.48) | ALKINSR | |
| SCHEMBL24179405 | 0.79 | EGFR (0.57) | ALK | |
| SCHEMBL31291051 | 0.79 | EGFR (0.57) | ALK | |
| SCHEMBL24178983 | 0.78 | EGFR (0.58) | ALKINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4177258-A1 | ARYLPHOSPHINE OXIDE COMPOUNDS AND USE THEREOF | Chengdu Di'Ao Jiuhong Pharmaceutical Factory (CN) | 2023-05-10 | — | — | EP | disclosed |