Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL253711 | 0.89 | GRM5 (0.74) | GRM5CYP2C9 | |
| SCHEMBL174130 | 0.88 | GRM5 (0.67) | GRM5CYP2C9 | |
| SCHEMBL254067 | 0.87 | GRM5 (0.73) | GRM5CYP2C9 | |
| SCHEMBL156930 | 0.87 | GRM5 (0.80) | GRM5CYP2C9 | |
| SCHEMBL173566 | 0.86 | GRM5 (0.65) | GRM5CYP2C9 | |
| SCHEMBL10246588 | 0.86 | GRM5 (0.72) | GRM5CYP2C9 | |
| SCHEMBL255028 | 0.86 | GRM5 (0.69) | GRM5CYP2C9 | |
| SCHEMBL157534 | 0.85 | GRM5 (0.91) | GRM5CYP2C9 | |
| SCHEMBL158611 | 0.85 | GRM5 (0.85) | GRM5CYP2C9 | |
| SCHEMBL160892 | 0.85 | GRM5 (0.68) | GRM5CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031024-A1 | BICYCLIC OXAZOLE AND THIAZOLE COMPOUNDS AND THEIR USE AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | VANDERBILT UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |