Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.31 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24649692 | 0.81 | HTR2A (0.43) | PARP1PIK3CGKMT2AHTR2AHTR2C | |
| SCHEMBL29209082 | 0.79 | BRD4 (0.42) | PARP1PIK3CGPIK3CDPIK3R1KMT2A | |
| SCHEMBL21608292 | 0.77 | PARP1 (0.40) | PARP1KMT2AATAD2 | |
| SCHEMBL29313927 | 0.76 | HTR2A (0.37) | PARP1PIK3CGPIK3CDPIK3R1HTR2A | |
| SCHEMBL12714874 | 0.74 | PARP1 (0.63) | PARP1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL26667753 | 0.71 | PARP1 (0.37) | PARP1 | |
| SCHEMBL31239530 | 0.70 | FLT3 (0.33) | PARP1 | |
| SCHEMBL12641837 | 0.70 | PARP1 (0.41) | PARP1KMT2A | |
| SCHEMBL866520 | 0.69 | CYP1A2 (0.34) | HSD17B10 | |
| SCHEMBL30605804 | 0.69 | CYP1A2 (0.34) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |