SCHEMBL25463535

SCHEMBL25463535

BC1(C(C)C)CCCCCCCC1C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25463413 0.83
SCHEMBL3885883 0.74
SCHEMBL21431988 0.68 MAPT (0.32) MAPT
SCHEMBL17895049 0.68 MAPT (0.32) MAPT
SCHEMBL21936312 0.67
SCHEMBL3899073 0.67
SCHEMBL9766871 0.67 MAPT (0.38) MAPT
SCHEMBL8766655 0.64 GAA (0.34) MAPT
SCHEMBL3035968 0.64 GAA (0.34) MAPT
SCHEMBL3713513 0.64 GAA (0.34) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023083297-A1 SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF INSILICO MEDICINE IP LIMITED (CN) 2023-05-19 WO disclosed
WO-2023083285-A1 SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF INSILICO MEDICINE IP LIMITED (CN) 2023-05-19 WO disclosed