Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.54 |
| ▸ | CSF1R | P07333 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 3/20 | 0.47 |
| ▸ | KDR | P35968 | 3/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAK | O14976 | 1/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
| ▸ | STK10 | O94804 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.43 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25468138 | 1.00 | EGFR (0.54) | EGFRCSF1RMAPTGRM1LCK | |
| SCHEMBL25464965 | 0.85 | GAK (0.49) | MAPTKDRHTTGAKRIPK2 | |
| SCHEMBL30417135 | 0.85 | GAK (0.49) | MAPTKDRHTTGAKRIPK2 | |
| SCHEMBL25466677 | 0.85 | GAK (0.49) | MAPTKDRHTTGAKRIPK2 | |
| SCHEMBL25201258 | 0.85 | GAK (0.49) | MAPTKDRHTTGAKRIPK2 | |
| SCHEMBL25466633 | 0.85 | GAK (0.49) | MAPTKDRHTTGAKRIPK2 | |
| SCHEMBL25468827 | 0.85 | GAK (0.49) | MAPTKDRHTTGAKRIPK2 | |
| SCHEMBL24028615 | 0.84 | EGFR (0.63) | EGFRCSF1RMAPTGRM1LCK | |
| SCHEMBL30417165 | 0.84 | EGFR (0.63) | EGFRCSF1RMAPTGRM1LCK | |
| SCHEMBL30416308 | 0.84 | EGFR (0.63) | EGFRCSF1RMAPTGRM1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086638-A1 | ENPP1 MODULATORS AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |