Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 15/20 | 0.49 |
| ▸ | BIRC2 | Q13490 | 9/20 | 0.44 |
| ▸ | BIRC3 | Q13489 | 3/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25470443 | 1.00 | XIAP (0.49) | XIAPBIRC2BIRC3ACEAPP | |
| Hydrochloric Acid SCHEMBL25167068 | 0.99 | XIAP (0.48) | XIAPBIRC2BIRC3ACEAPP | |
| Hydrochloric Acid SCHEMBL25167069 | 0.99 | XIAP (0.48) | XIAPBIRC2BIRC3ACEAPP | |
| Hydrochloric Acid SCHEMBL25167070 | 0.99 | XIAP (0.48) | XIAPBIRC2BIRC3ACEAPP | |
| SCHEMBL25468798 | 0.90 | XIAP (0.61) | XIAPBIRC2BIRC3 | |
| SCHEMBL25470448 | 0.90 | XIAP (0.61) | XIAPBIRC2BIRC3 | |
| Hydrochloric Acid SCHEMBL25172116 | 0.89 | XIAP (0.60) | XIAPBIRC2BIRC3 | |
| SCHEMBL25472261 | 0.87 | XIAP (0.43) | XIAP | |
| SCHEMBL25469540 | 0.87 | XIAP (0.59) | XIAPBIRC2BIRC3 | |
| SCHEMBL23979095 | 0.86 | XIAP (0.49) | XIAPBIRC2BIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081290-A1 | INHIBITOR OF APOPTOSIS (IAP) PROTEIN ANTAGONISTS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2023-05-11 | — | — | WO | disclosed |