Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 8/20 | 0.65 |
| ▸ | LCK | P06239 | 3/20 | 0.65 |
| ▸ | LYN | P07948 | 1/20 | 0.65 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.64 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.64 |
| ▸ | SRC | P12931 | 10/20 | 0.62 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 10/20 | 0.61 |
| ▸ | KDR | P35968 | 9/20 | 0.61 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.61 |
| ▸ | ABL1 | P00519 | 7/20 | 0.61 |
| ▸ | HCK | P08631 | 7/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.61 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.61 |
| ▸ | MTOR | P42345 | 7/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.61 |
| ▸ | EPHB4 | P54760 | 7/20 | 0.61 |
| ▸ | PRKDC | P78527 | 7/20 | 0.61 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.61 |
| ▸ | TEK | Q02763 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30415789 | 0.89 | BTK (0.68) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL24196857 | 0.89 | BTK (0.68) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL30415747 | 0.89 | BTK (0.65) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL24196897 | 0.89 | BTK (0.65) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL5801169 | 0.88 | BTK (0.82) | BTKLCKLYNNUDT14NUDT5 | |
| Hydrochloric Acid SCHEMBL21331506 | 0.88 | BTK (0.81) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL25933038 | 0.86 | BTK (0.66) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL25934984 | 0.86 | BTK (0.66) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL24196604 | 0.85 | BTK (0.68) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL25466297 | 0.85 | BTK (0.68) | BTKLCKLYNNUDT14NUDT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180432-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-05-17 | — | — | EP | disclosed |