Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 12/20 | 0.71 |
| ▸ | BTK | Q06187 | 9/20 | 0.68 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.68 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.68 |
| ▸ | LCK | P06239 | 5/20 | 0.64 |
| ▸ | LYN | P07948 | 1/20 | 0.64 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | TEK | Q02763 | 1/20 | 0.61 |
| ▸ | CSK | P41240 | 2/20 | 0.59 |
| ▸ | EGFR | P00533 | 2/20 | 0.58 |
| ▸ | ITK | Q08881 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22720988 | 0.92 | BTK (0.80) | SRCBTKNUDT14NUDT5LCK | |
| SCHEMBL24197177 | 0.89 | BTK (0.85) | SRCBTKNUDT14NUDT5LCK | |
| SCHEMBL25466299 | 0.87 | BTK (0.80) | SRCBTKNUDT14NUDT5LCK | |
| SCHEMBL25933034 | 0.86 | BTK (0.68) | SRCBTKNUDT14NUDT5LCK | |
| SCHEMBL24197056 | 0.86 | BTK (0.68) | SRCBTKNUDT14NUDT5LCK | |
| SCHEMBL25466297 | 0.85 | BTK (0.68) | SRCBTKNUDT14NUDT5LCK | |
| SCHEMBL25933741 | 0.84 | BTK (0.66) | SRCBTKNUDT14NUDT5LCK | |
| SCHEMBL25933743 | 0.84 | BTK (0.66) | SRCBTKNUDT14NUDT5LCK | |
| SCHEMBL25933729 | 0.84 | BTK (0.62) | SRCBTKNUDT14NUDT5LCK | |
| SCHEMBL14617312 | 0.83 | SRC (1.00) | SRCLCKKDRCSKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180432-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-05-17 | — | — | EP | disclosed |