⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15865212 | 0.62 | — | — | |
| SCHEMBL12150170 | 0.62 | — | — | |
| SCHEMBL10713533 | 0.62 | — | — | |
| SCHEMBL14327500 | 0.62 | — | — | |
| SCHEMBL8267240 | 0.62 | — | — | |
| SCHEMBL11751205 | 0.62 | — | — | |
| SCHEMBL9609373 | 0.62 | — | — | |
| SCHEMBL6656462 | 0.62 | — | — | |
| SCHEMBL13617273 | 0.62 | — | — | |
| SCHEMBL1869500 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382916-A | The high purity synthetic process of 3 tetrahydrofurfuryl carbinols | 成都化润药业有限公司 | 2017-11-24 | — | — | CN | claimed |
| US-8778958-B2 | Synthesis of metabolically stable agents for alcohol and drug abuse | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2014-07-15 | — | — | US | claimed |
| US-20110263630-A1 | SYNTHESIS OF METABOLICALLY STABLE AGENTS FOR ALCOHOL AND DRUG ABUSE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2011-10-27 | — | — | US | claimed |
| WO-2023147312-A1 | AMPK AGONISTS AND METHODS OF USE THEREOF | EVVIA THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| EP-3131897-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2022-06-15 | — | — | EP | disclosed |
| EP-3131896-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2019-01-30 | — | — | EP | disclosed |
| US-10000476-B2 | Pyridone derivative, pharmaceutical containing the same and methods of use thereof | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2018-06-19 | — | — | US | disclosed |
| US-9969724-B2 | Factor IXa inhibitors | MERCK SHARP & DOHME CORP. (US) | 2018-05-15 | — | — | US | disclosed |
| EP-2789607-B1 | PYRIDONE DERIVATIVE AND MEDICINE CONTAINING SAME | KAKEN PHARMA CO LTD (JP) | 2018-02-07 | — | — | EP | disclosed |
| US-9808445-B2 | Factor IXa inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-11-07 | — | — | US | disclosed |
| US-20170129880-A1 | FACTOR IXa INHIBITORS | MERCK SHARP & DOHME LLC | 2017-05-11 | — | — | US | disclosed |
| WO-2003011885-A1 | NON-NATURAL CARBON-LINKED NUCLEOTIDES AND DINUCLEOTIDES | CELLTECH R & D LIMITED (GB) | 2003-02-13 | — | — | WO | disclosed |
| US-6472345-B2 | TITANIUM HALIDES, SULFONATES OR DIOLATES | SOLVIAS AG (CH) | 2002-10-29 | — | — | US | disclosed |
| WO-2002062816-A1 | NON-NATURAL NUCLEOTIDES AND DINUCLEOTIDES | CELLTECH R & D LIMITED (GB) | 2002-08-15 | — | — | WO | disclosed |
| EP-1187798-A1 | PRODUCTION OF OPTICALLY ACTIVE $g(a)-HYDROXYACETALS | Solvias AG (CH) | 2002-03-20 | — | — | EP | disclosed |
| US-20020026067-A1 | Catalytic halogenation of activated methylene and methine compounds | SOLVIAS AG (CH) | 2002-02-28 | — | — | US | disclosed |
| EP-1151980-A1 | Catalytic halogenation of activated methylene and methine compound | Solvias AG (CH) | 2001-11-07 | — | — | EP | disclosed |
| US-20010037042-A1 | Coupling of nucleophiles, vinyl compounds or CO with water, alcohols or amines to organic compounds | SOLVIAS AG (CH) | 2001-11-01 | — | — | US | disclosed |
| EP-1132361-A1 | Coupling of nucleophiles, vinyl compounds or CO with water, alcohols or amines to organic compounds | Solvias AG (CH) | 2001-09-12 | — | — | EP | disclosed |
| WO-2001000545-A1 | PRODUCTION OF OPTICALLY ACTIVE α-HYDROXYACETALS | SOLVIAS AG (CH) | 2001-01-04 | — | — | WO | disclosed |