⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787798 | 0.72 | MEN1 (0.30) | — | |
| SCHEMBL18829872 | 0.71 | — | — | |
| SCHEMBL4358910 | 0.69 | — | — | |
| SCHEMBL457251 | 0.69 | — | — | |
| SCHEMBL29306916 | 0.66 | — | — | |
| SCHEMBL24936344 | 0.65 | MEN1 (0.31) | — | |
| SCHEMBL25541675 | 0.65 | — | — | |
| SCHEMBL27110116 | 0.65 | — | — | |
| SCHEMBL12139939 | 0.65 | — | — | |
| SCHEMBL24843811 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |