Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25477743 | 0.93 | TSHR (0.58) | TSHRMAPTNPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL25477767 | 0.93 | TSHR (0.60) | TSHRMAPTNPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL25477739 | 0.93 | TSHR (0.60) | TSHRMAPTNPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL25477801 | 0.93 | TSHR (0.63) | TSHRMAPTNPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL25477779 | 0.91 | TSHR (0.58) | TSHRMAPTNPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL25477795 | 0.91 | TSHR (0.58) | TSHRMAPTNPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL25477969 | 0.91 | TSHR (0.60) | TSHRMAPTNPSR1SMN1; SMN2EPHX1 | |
| SCHEMBL25477787 | 0.89 | TSHR (0.58) | TSHRMAPTNPSR1SMN1; SMN2EPHX1 | |
| SCHEMBL25477798 | 0.88 | TSHR (0.63) | TSHRMAPTNPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14094718 | 0.87 | TSHR (0.62) | TSHRMAPTEPHX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151136-A1 | CATALYST COMPOSITION FOR POLYURETHANES | MOMENTIVE PERFORMANCE MATERIALS INC. | 2023-05-18 | — | — | US | disclosed |
| US-20230151136-A1 | CATALYST COMPOSITION FOR POLYURETHANES | MOMENTIVE PERFORMANCE MATERIALS INC. | 2023-05-18 | — | — | US | disclosed |