SCHEMBL25480263

SCHEMBL25480263

c1ccc(-c2ccc(-c3ccc(-n4c5ccccc5c5c6c7cccc8c9ccccc9n(c6ccc54)c87)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ATM Q13315 1/20 0.46
HDAC4 P56524 1/20 0.39
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
HTT P42858 2/20 0.34
IL1R1 P14778 1/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
PTPN1 P18031 2/20 0.32
PDE6D O43924 1/20 0.31
DUSP3 P51452 1/20 0.31
ALKBH5 Q6P6C2 1/20 0.30
FTO Q9C0B1 1/20 0.30
JAK2 O60674 1/20 0.30
JAK3 P52333 1/20 0.30
AKR1C4 P17516 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25480323 1.00 KDM4E (0.46) KDM4EL3MBTL1ATMHDAC4KMT2A
SCHEMBL21453600 0.99 KDM4E (0.45) KDM4EL3MBTL1ATMHDAC4KMT2A
SCHEMBL20071693 0.95 KDM4E (0.44) KDM4EL3MBTL1ATMHDAC4KMT2A
SCHEMBL17995030 0.92 KDM4E (0.44) KDM4EL3MBTL1ATMHDAC4KMT2A
SCHEMBL17995017 0.92 KDM4E (0.44) KDM4EL3MBTL1ATMHDAC4KMT2A
SCHEMBL25635032 0.91 KDM4E (0.56) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL12281290 0.91 KDM4E (0.56) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL25635047 0.91 KDM4E (0.56) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL24703283 0.91 KDM4E (0.41) KDM4EL3MBTL1ATMHDAC4KMT2A
SCHEMBL25480279 0.91 ATM (0.42) KDM4EL3MBTL1ATMHDAC4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 KDM4E 2090/4885L3MBTL1 888/4885ATM 3709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.