Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 14/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25482113 | 0.88 | KDR (0.34) | KDRSYKSMN1; SMN2MEN1LMNA | |
| SCHEMBL25467362 | 0.88 | KDR (0.34) | KDRSYKSMN1; SMN2MEN1LMNA | |
| SCHEMBL25515430 | 0.86 | KDR (0.34) | KDRSYKSMN1; SMN2MEN1LMNA | |
| SCHEMBL25467455 | 0.86 | KDR (0.33) | KDRSYKSMN1; SMN2MEN1LMNA | |
| SCHEMBL25467404 | 0.85 | KDR (0.34) | KDRSYKSMN1; SMN2MEN1LMNA | |
| SCHEMBL25467454 | 0.85 | KDR (0.34) | KDRSYKSMN1; SMN2MEN1LMNA | |
| SCHEMBL25515289 | 0.84 | KDR (0.34) | KDRSYKSMN1; SMN2MEN1LMNA | |
| SCHEMBL25467817 | 0.84 | KDR (0.36) | KDRSYKSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL25467361 | 0.83 | KDR (0.33) | KDRSYKSMN1; SMN2MEN1LMNA | |
| SCHEMBL25481999 | 0.83 | KDR (0.33) | KDRSYKSMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |