⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2426255 | 1.00 | — | — | |
| SCHEMBL12126946 | 1.00 | — | — | |
| SCHEMBL9613647 | 0.90 | EPHX1 (0.30) | — | |
| SCHEMBL11378272 | 0.90 | EPHX1 (0.30) | — | |
| SCHEMBL11836323 | 0.87 | — | — | |
| SCHEMBL7363310 | 0.79 | — | — | |
| SCHEMBL18611198 | 0.79 | — | — | |
| SCHEMBL685314 | 0.79 | — | — | |
| SCHEMBL18611197 | 0.79 | — | — | |
| SCHEMBL9720381 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230340328-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-10-26 | — | — | US | disclosed |
| US-20230340328-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-10-26 | — | — | US | disclosed |
| WO-2023086799-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2021226629-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | AMGEN INC. (US) | 2021-11-11 | — | — | WO | disclosed |
| EP-2970114-B1 | IDO INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2019-05-15 | — | — | EP | disclosed |
| EP-2970155-B1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE (IDO) | BRISTOL MYERS SQUIBB CO (US) | 2018-04-25 | — | — | EP | disclosed |
| WO-2018048969-A1 | MULTI-TARGETED HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-03-15 | — | — | WO | disclosed |
| US-9809521-B2 | Cannabidinoid derivatives | SUTTER WEST BAY HOSPITALS (US) | 2017-11-07 | — | — | US | disclosed |
| US-9802952-B2 | Method and apparatus for the synthesis of dihydroartemisinin and artemisinin derivatives | Max-Plank-Gesellschaft zur Förderung der Wissenschaften e.v. (DE) | 2017-10-31 | — | — | US | disclosed |
| US-9802952-B2 | Method and apparatus for the synthesis of dihydroartemisinin and artemisinin derivatives | Max-Plank-Gesellschaft zur Förderung der Wissenschaften e.v. (DE) | 2017-10-31 | — | — | US | disclosed |
| EP-0852225-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS AND MEDICINAL PREPARATIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | NIPPON STEEL CORPORATION (JP) | 1998-07-08 | — | — | EP | disclosed |
| EP-0800516-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996020172-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED β-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1996-07-04 | — | — | WO | disclosed |
| CN-1099740-A | Selective catalytic hydrogenation of aromatic aldehydes | DEGUSSA (DE) | 1995-03-08 | — | — | CN | disclosed |
| US-5387726-A | Selective catalytic hydrogenation of aromatic aldehydes | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1995-02-07 | — | — | US | disclosed |
| EP-0606072-A1 | Selective catalytic hydrogenation of aromatic aldehydes | Degussa Aktiengesellschaft (DE) | 1994-07-13 | — | — | EP | disclosed |
| EP-0352299-A1 | RUBRADIRIN DERIVATIVES FOR TREATMENT OF HIV INFECTION | THE UPJOHN COMPANY (US) | 1990-01-31 | — | — | EP | disclosed |
| WO-1988008707-A2 | RUBRADIRIN DERIVATIVES FOR TREATMENT OF HIV INFECTION | THE UPJOHN COMPANY (US) | 1988-11-17 | — | — | WO | disclosed |
| US-4163789-A | Anti-psychotic (cycloalkenylalkylpiperidino) benzamides | ANPHAR, S.A. (ES) | 1979-08-07 | — | — | US | disclosed |
| US-3971825-A | (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS | SANKYO COMPANY LIMITED (JA) | 1976-07-27 | — | — | US | disclosed |