Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25485125 | 0.91 | ADORA2A (0.40) | ADORA2APIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL25485624 | 0.90 | PIM1 (0.43) | ADORA2APIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL25484253 | 0.88 | PIM1 (0.43) | ADORA2APIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL25177539 | 0.88 | PIM1 (0.45) | ADORA2APIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL31758995 | 0.88 | PIM1 (0.45) | ADORA2APIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL25484884 | 0.86 | ADORA2A (0.41) | ADORA2APIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL25484779 | 0.85 | PIM1 (0.43) | ADORA2APIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL25485628 | 0.83 | ADORA2A (0.40) | ADORA2APIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL25485003 | 0.83 | ADORA2A (0.39) | ADORA2APIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL25485004 | 0.83 | PIM1 (0.40) | ADORA2APIM1CSNK2A2CSNK2BPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078812-A1 | BENZOFURO[3,2-D]PYRIMIDINO-2,4-DICARBONITRIL DERIVATIVES AND SIMILAR COMPOUNDS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2023-05-11 | — | — | WO | disclosed |