Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3784721 | 1.00 | FFAR3 (0.54) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL587435 | 1.00 | FFAR3 (0.54) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL20764 | 0.96 | — | — | |
| Acetic Acid SCHEMBL28823872 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL4820061 | 0.92 | — | — | |
| Acetic Acid SCHEMBL28805023 | 0.92 | — | — | |
| Acetic Acid SCHEMBL5928939 | 0.86 | FFAR3 (0.47) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL11710390 | 0.85 | FFAR3 (0.54) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL6150066 | 0.85 | FFAR3 (0.54) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL21145157 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341884-A1 | GREASE CUTTING LIGHT DUTY LIQUID DETERGENT | Colgate-Palmolive Company (US) | 2003-09-10 | — | — | EP | claimed |
| US-20030150068-A1 | Dye-accelerant composition and process for using same | JUNG JAMES (US) | 2003-08-14 | — | — | US | claimed |
| US-20030005528-A1 | Dye-accelerant composition and process for using same | SILLA AMERICA, INC. | 2003-01-09 | — | — | US | claimed |
| WO-2002092905-A1 | DYE-ACCELERANT COMPOSITION AND PROCESS FOR USING SAME | JUNG JAMES (US) | 2002-11-21 | — | — | WO | claimed |
| WO-2002066590-A1 | GREASE CUTTING LIGHT DUTY LIQUID DETERGENT | COLGATE-PALMOLIVE COMPANY (US) | 2002-08-29 | — | — | WO | claimed |
| US-6331516-B1 | FOAMING; HARD SURFACE CLEANERS | COLGATE PALMOLIVE COMPANY | 2001-12-18 | — | — | US | claimed |
| US-6291419-B1 | PARAFFIN SULFONATE, AN ALPHA OLEFIN SULFONATE, AN AMINE OXIDE, WATER. | COLGATE-PALMOLIVE CO. | 2001-09-18 | — | — | US | claimed |
| EP-0541317-A1 | A method of scavenging oxygen from boiler waters with substituted quinolines | NALCO CHEMICAL COMPANY (US) | 1993-05-12 | — | — | EP | claimed |
| US-5167835-A | Providing corrosion resistance, prevention of scale | NALCO CHEMICAL COMPANY (US) | 1992-12-01 | — | — | US | claimed |
| WO-2011121291-A1 | DECONTAMINATION METHOD | UNIVERSITY OF DUNDEE (GB) | 2011-10-06 | — | — | WO | disclosed |
| US-6627108-B1 | Salicylic acid, nitrilotriacetic acid, sodium hydroxide, n,n-di-secbutylaminophenol, polyalkylene methylpolysiloxane and water; efficient elemental sulfur recovery | INSTITUT FRANCAIS DU PETROLE (FR) | 2003-09-30 | — | — | US | disclosed |
| US-20030150068-A1 | Dye-accelerant composition and process for using same | JUNG JAMES (US) | 2003-08-14 | — | — | US | disclosed |
| US-6602304-B2 | Comprising an organic solvent, dispersing agent(s), a chelating agent, and a vehicle, water; impregnating a fiber with a dye-accelerant and then applying the reactive dye; uniformity; kinetics; continuous processing | SILLA AMERICA, INC. | 2003-08-05 | — | — | US | disclosed |
| US-20030005528-A1 | Dye-accelerant composition and process for using same | SILLA AMERICA, INC. | 2003-01-09 | — | — | US | disclosed |
| WO-2002092905-A1 | DYE-ACCELERANT COMPOSITION AND PROCESS FOR USING SAME | JUNG JAMES (US) | 2002-11-21 | — | — | WO | disclosed |
| US-5929009-A | Liquid detergent composition containing amine oxide | COLGATE PALMOLIVE CO. (US) | 1999-07-27 | — | — | US | disclosed |
| US-4605809-A | Aluminosilicates and silica gels having a low content of transition elements, a process for their use in the conversion of methanol to olefins | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-08-12 | — | — | US | disclosed |