Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GRN | P28799 | 3/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16279245 | 0.81 | KDM4E (0.41) | KDM4EGRNSORT1POLBCNR1 | |
| SCHEMBL3198150 | 0.77 | KDM4E (0.37) | KDM4EGRNSORT1CNR1CNR2 | |
| SCHEMBL283910 | 0.76 | KDM4E (0.44) | KDM4EGRNSORT1POLBCNR1 | |
| SCHEMBL284110 | 0.76 | CNR1 (0.40) | KDM4EGRNSORT1CNR1CNR2 | |
| SCHEMBL1924672 | 0.74 | KDM4E (0.42) | KDM4EGRNSORT1POLBCNR1 | |
| SCHEMBL282922 | 0.73 | CNR1 (0.49) | KDM4EGRNSORT1CNR1CNR2 | |
| SCHEMBL22505758 | 0.73 | KDM4E (0.41) | KDM4EGRNSORT1POLBCNR1 | |
| SCHEMBL3843249 | 0.72 | KDM4E (0.46) | KDM4EGRNSORT1POLBCNR1 | |
| SCHEMBL284523 | 0.72 | KDM4E (0.41) | KDM4EGRNSORT1POLBCNR1 | |
| SCHEMBL15007149 | 0.72 | CNR1 (0.42) | KDM4EGRNSORT1POLBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424924-B1 | UREA COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) | 2023-05-24 | — | — | EP | disclosed |