Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22416420 | 0.89 | KDM4E (0.57) | HRH3KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL30340903 | 0.89 | MAOB (0.60) | HRH3KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL5912588 | 0.85 | HRH3 (0.66) | HRH3KDM4EALDH1A1MAPK1TDP1 | |
| SCHEMBL30771666 | 0.85 | HRH3 (0.53) | HRH3KDM4EKMT2AALDH1A1ALOX15 | |
| SCHEMBL30771670 | 0.85 | HRH3 (0.53) | HRH3KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL30771680 | 0.85 | MAOB (0.53) | HRH3KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL4215600 | 0.83 | HRH3 (0.67) | HRH3KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL3973187 | 0.83 | HRH3 (0.67) | HRH3KDM4EALDH1A1TDP1RAB9A | |
| SCHEMBL30771691 | 0.82 | HRH3 (0.50) | HRH3KDM4EKMT2AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL3972282 | 0.82 | HRH3 (0.65) | HRH3KDM4EALDH1A1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088620-A1 | CYCLIC BIARYL PHOSPHINES AS LIGANDS FOR PALLADIUM-CONTAINING CATALYSTS IN CROSS-COUPLING REACTIONS | Heraeus Deutschland GmbH & Co. KG (DE) | 2023-05-25 | — | — | WO | disclosed |
| EP-4180440-A1 | CYCLIC BIARYLPHOSPHINES AS LIGANDS FOR PALLADIUM-CONTAINING CATALYSTS IN CROSS-COUPLING REACTIONS | Heraeus Deutschland GmbH & Co. KG (DE) | 2023-05-17 | — | — | EP | disclosed |