Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29565166 | 0.89 | PIM1 (0.54) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL24388208 | 0.89 | PIM1 (0.54) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL26819559 | 0.85 | PIM1 (0.41) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL25490379 | 0.82 | SMN1; SMN2 (0.37) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL22006945 | 0.80 | KMT2A (0.49) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL24388220 | 0.80 | AHR (0.43) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL1310612 | 0.80 | SMN1; SMN2 (0.62) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL26819636 | 0.79 | PIM1 (0.39) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL20030116 | 0.78 | SMN1; SMN2 (0.49) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL24388438 | 0.78 | PIM1 (0.38) | PIM1CSNK2A2CSNK2BPIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078812-A1 | BENZOFURO[3,2-D]PYRIMIDINO-2,4-DICARBONITRIL DERIVATIVES AND SIMILAR COMPOUNDS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2023-05-11 | — | — | WO | disclosed |