SCHEMBL2549182

SCHEMBL2549182

N=C(Cl)c1ccccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3055506 0.97 BLM (0.55)
SCHEMBL27398393 0.78 CES1 (0.61)
Benzamidine SCHEMBL650254 0.77 F2 (0.89)
SCHEMBL3940726 0.73 TSHR (0.56)
SCHEMBL3940728 0.73 TSHR (0.56)
SCHEMBL98370 0.73
SCHEMBL16814995 0.73 F2 (0.58)
SCHEMBL1306184 0.73
SCHEMBL1193713 0.73 CES1 (0.47)
Benzamide SCHEMBL30081945 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4232151-A ANTIBIOTICS SHIONOGI & CO., LTD. (JP) 1980-11-04 US claimed
CN-118717618-A Facial mask containing lonicera japonica components and processing method thereof 怀化市九天界生态农业科技有限公司 2024-10-01 CN disclosed
CN-118206478-A Chiral/racemic pyrroline sulfide and synthesis and application thereof 湖大粤港澳大湾区创新研究院(广州增城) 2024-06-18 CN disclosed
CN-111868042-B Herbicidal 3-phenylisoxazoline-5-carboxamides of cyclopentylcarboxylic acid derivatives 拜耳公司 2023-12-05 CN disclosed
CN-110678450-B Isoxazole derivatives as nuclear receptor agonists and uses thereof 日东制药株式会社 2023-06-20 CN disclosed
CN-108658816-B N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides 拜尔农作物科学股份公司 2023-05-02 CN disclosed
WO-2021079962-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTION AND/OR TREATMENT OF HEARING LOSS 国立大学法人大阪大学 2021-04-29 WO disclosed
US-10906890-B2 Triazole phenyl compounds as agonists of the APJ receptor AMGEN INC. (US) 2021-02-02 US disclosed
EP-3438114-B1 METAL COMPLEX, COMPOSITION AND LIGHT-EMITTING DEVICE SUMITOMO CHEMICAL CO (JP) 2020-11-04 EP disclosed
CN-111868042-A Herbicidally active 3-phenylisoxazoline-5-carboxamides of cyclopentyl carboxylic acid derivatives 拜耳公司 2020-10-30 CN disclosed
US-4450217-A CHARGE GENERATION LAYER CONTAINING SELIUM- OR TELLURIUM-CONTAINING SENSITIZERS EASTMAN KODAK COMPANY (US) 1984-05-22 US disclosed
EP-0051067-A1 TRIAZINE SYNTHESIS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1982-05-12 EP disclosed
US-4304914-A CARDIOTONIC AGENTS, HYPOTENSIVE AGENTS USV PHARMACEUTICAL CORPORATION (US) 1981-12-08 US disclosed
US-4302591-A 1-BENZIMIDOYL-DIHYDROPYRIDINES USV PHARMACEUTICAL CORPORATION (US) 1981-11-24 US disclosed
WO-1981003020-A1 TRIAZINE SYNTHESIS COMMW SCIENT IND RES ORG (AU) 1981-10-29 WO disclosed
US-4264505-A ANTIARRHYTHMIA AGENTS USV PHARMACEUTICAL CORPORATION (US) 1981-04-28 US disclosed
US-4058532-A 1-Phenyl-3,4-dihydrocarbostyrils STERLING DRUG INC. (US) 1977-11-15 US disclosed
US-4049715-A 3-[2-(4-Anisidino)phenyl]-1-phenyl-1-propiophenones and propanols STERLING DRUG INC. (US) 1977-09-20 US disclosed
US-4029815-A Anti-diarrheal anthranilic acids SCHERING CORPORATION (US) 1977-06-14 US disclosed
US-3994902-A Certain 1,2-diphenyl-1,2,3,4-tetrahydroquinoline compounds STERLING DRUG INC. (US) 1976-11-30 US disclosed