Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25197305 | 0.98 | POLB (0.37) | POLBNISCHRNASELMEN1KMT2A | |
| SCHEMBL10832383 | 0.72 | POLB (0.42) | POLBRNASELMEN1KMT2ALMNA | |
| SCHEMBL11786446 | 0.68 | NPC1 (0.56) | POLBRNASELMEN1KMT2ALMNA | |
| SCHEMBL4130846 | 0.65 | POLB (0.52) | POLBMEN1KMT2ALMNAMAPT | |
| SCHEMBL14256813 | 0.63 | POLB (0.50) | POLBMEN1KMT2ALMNAMAPT | |
| SCHEMBL18434711 | 0.63 | POLB (0.50) | POLBMEN1KMT2ALMNAMAPT | |
| SCHEMBL31356867 | 0.62 | POLB (0.49) | POLBMEN1KMT2ALMNAMAPT | |
| SCHEMBL1535338 | 0.62 | POLB (0.49) | POLBMEN1KMT2ALMNAMAPT | |
| SCHEMBL112040 | 0.60 | — | — | |
| SCHEMBL13725034 | 0.60 | POLB (0.61) | POLBMEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023084054-A1 | TREATMENT OF ADHD USING SELECTIVE BINDERS OF THE 11-IMIDAZOLINE RECEPTOR | 3Z EHF (IS) | 2023-05-19 | — | — | WO | disclosed |