SCHEMBL2549533

SCHEMBL2549533

C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MME P08473 6/20 0.60
ACE P12821 6/20 0.60
CPA1 P15085 1/20 0.60
ACE2 Q9BYF1 1/20 0.60
FOLH1 Q04609 1/20 0.58
OPRD1 P41143 5/20 0.53
OPRM1 P35372 4/20 0.53
OPRK1 P41145 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30445690 1.00 MME (0.60) MMEACECPA1ACE2FOLH1
SCHEMBL2493049 0.94 ACE (0.65) MMEACECPA1ACE2FOLH1
SCHEMBL4073351 0.94 ACE (0.65) MMEACECPA1ACE2FOLH1
SCHEMBL2545591 0.94 ACE (0.65) MMEACECPA1ACE2FOLH1
SCHEMBL31287928 0.94 ACE (0.65) MMEACECPA1ACE2FOLH1
Water SCHEMBL20489335 0.93 ACE (0.64) MMEACECPA1ACE2FOLH1
Water SCHEMBL20495306 0.93 ACE (0.64) MMEACECPA1ACE2FOLH1
Water SCHEMBL20489337 0.93 ACE (0.64) MMEACECPA1ACE2FOLH1
Water SCHEMBL29167823 0.93 ACE (0.64) MMEACECPA1ACE2FOLH1
Water SCHEMBL29167817 0.93 ACE (0.64) MMEACECPA1ACE2FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2007348-B1 PAEDIATRIC AMINO ACID SOLUTION FOR PARENTERAL NUTRITION FRESENIUS KABI DE GMBH (DE) 2014-12-10 EP claimed
US-12527851-B2 Methods and materials for treating cancer MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2026-01-20 US disclosed
US-11911455-B2 HPV therapeutic nucleic acid vaccine BEIJING AEONVITAL BIOMEDICINE RESEARCH CO., LTD. (CN) 2024-02-27 US disclosed
US-20240009294-A1 HPV Therapeutic Nucleic Acid Vaccine BEIJING AEONVITAL BIOMEDICINE RESEARCH CO., LTD. (CN) 2024-01-11 US disclosed
EP-4252852-A2 METHODS AND MATERIALS FOR TREATING CANCER Mayo Foundation for Medical Education and Research (US) 2023-10-04 EP disclosed
WO-2023142647-A1 NEW TYPE THERAPEUTIC NUCLEIC ACID VACCINE FOR HPV 北京循生生物医学研究有限公司 2023-08-03 WO disclosed
CN-114134165-B Novel HPV therapeutic nucleic acid vaccine 北京循生生物医学研究有限公司 2022-04-29 CN disclosed
CN-114134165-A Novel HPV therapeutic nucleic acid vaccine 北京循生生物医学研究有限公司 2022-03-04 CN disclosed
US-20110262962-A1 METHOD FOR PRODUCING PEPTIDES AJINOMOTO CO., INC. (JP) 2011-10-27 US disclosed
US-20070292916-A1 MUTANT PROTEIN HAVING THE PEPTIDE-SYNTHESIZING ACTIVITY AJINOMOTO CO., INC. (JP) 2007-12-20 US disclosed
CN-101087878-A Mutant protein having the peptide-synthesizing activity AJINOMOTO KK (JP) 2007-12-12 CN disclosed
EP-1829968-A1 MUTANT PROTEIN HAVING PEPTIDE-PRODUCTION ACTIVITY Ajinomoto Co., Inc. (JP) 2007-09-05 EP disclosed
US-20070190602-A1 Mutant protein having the peptide-synthesizing activity AJINOMOTO CO., INC (JP) 2007-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527851-B2 Methods and materials for treating cancer APOBEC3A, APOBEC3G, APOBEC3B MME 2354/4885ACE 3121/4885CPA1 224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.