Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 15/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26321380 | 0.91 | MAPKAPK2 (0.48) | MAPKAPK2SLC2A1MAPTPARP1 | |
| SCHEMBL23999518 | 0.89 | MAPKAPK2 (0.47) | MAPKAPK2SLC2A1PARP1 | |
| SCHEMBL30180429 | 0.86 | MAPKAPK2 (0.53) | MAPKAPK2SLC2A1MAPTMAPK10POLB | |
| SCHEMBL23999521 | 0.86 | MAPKAPK2 (0.53) | MAPKAPK2SLC2A1MAPTMAPK10POLB | |
| SCHEMBL26323527 | 0.86 | MAPT (0.49) | MAPKAPK2SLC2A1MAPTPOLBTSHR | |
| SCHEMBL25495751 | 0.84 | MAPKAPK2 (0.38) | MAPKAPK2SLC2A1 | |
| SCHEMBL23999907 | 0.83 | MAPKAPK2 (0.42) | MAPKAPK2 | |
| SCHEMBL26321385 | 0.82 | SLC2A1 (0.42) | MAPKAPK2SLC2A1MAPT | |
| SCHEMBL26321428 | 0.82 | MAPKAPK2 (0.40) | MAPKAPK2SLC2A1MAPK10 | |
| SCHEMBL23999835 | 0.81 | SLC2A1 (0.41) | MAPKAPK2SLC2A1MAPTMAPK10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |