Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19684302 | 0.88 | KMT2A (0.49) | TSHRKMT2AKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL15235747 | 0.88 | KMT2A (0.49) | TSHRKMT2AKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL13244990 | 0.87 | KMT2A (0.53) | TSHRKMT2AKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL13245463 | 0.86 | KMT2A (0.52) | TSHRKMT2AKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL3013062 | 0.82 | KMT2A (0.47) | TSHRKMT2AKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL15235766 | 0.82 | KMT2A (0.47) | TSHRKMT2AKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL13244735 | 0.81 | KMT2A (0.53) | TSHRKMT2AKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL13245364 | 0.80 | KMT2A (0.54) | TSHRKMT2AKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL13245461 | 0.80 | KMT2A (0.54) | TSHRKMT2AKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL13654204 | 0.79 | KMT2A (0.56) | TSHRKMT2AMAPK1SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031298-A2 | ETHYNYLBENZENE DERIVATIVES | DUKE UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |