SCHEMBL25501822

SCHEMBL25501822

CCC(C)C(=O)OCCOCCOc1ccc(C(=O)Oc2ccc(-c3ccc(OC)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.47
MAPT P10636 7/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
ALDH1A1 P00352 2/20 0.43
PKM P14618 1/20 0.43
PRSS1 P07477 1/20 0.41
ACR P10323 1/20 0.41
LMNA P02545 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
NPC1 O15118 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
KMT2A Q03164 2/20 0.40
RAB9A P51151 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25491873 1.00 RARB (0.47) RARBMAPTSMN1; SMN2ALDH1A1PKM
SCHEMBL25773225 1.00 RARB (0.47) RARBMAPTSMN1; SMN2ALDH1A1PKM
SCHEMBL761656 0.97 MAPT (0.47) MAPTSMN1; SMN2ALDH1A1PKMPRSS1
SCHEMBL27118098 0.97 MAPT (0.47) RARBMAPTSMN1; SMN2ALDH1A1PKM
SCHEMBL25802116 0.95 RARB (0.51) RARBMAPTSMN1; SMN2PRSS1ACR
SCHEMBL25802143 0.95 RARB (0.51) RARBMAPTSMN1; SMN2PRSS1ACR
SCHEMBL25501828 0.93 MAPT (0.53) RARBMAPTSMN1; SMN2ALDH1A1PRSS1
SCHEMBL25501844 0.93 MAPT (0.53) RARBMAPTSMN1; SMN2ALDH1A1PRSS1
SCHEMBL25501256 0.92 MAPT (0.46) MAPTSMN1; SMN2ALDH1A1PKMPRSS1
SCHEMBL23136692 0.92 MAPT (0.48) RARBMAPTSMN1; SMN2ALDH1A1PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11822180-B2 Polarizer and image display device FUJIFILM CORPORATION (JP) 2023-11-21 US disclosed
US-20230265346-A1 LIQUID CRYSTAL COMPOSITION, OPTICALLY ANISOTROPIC LAYER, LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-08-24 US disclosed
US-20230159827-A1 LIQUID CRYSTAL COMPOSITION, FLUORINE-CONTAINING POLYMER, OPTICALLY ANISOTROPIC LAYER, LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-05-25 US disclosed