⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254474 | 0.71 | — | — | |
| SCHEMBL22990391 | 0.70 | BRD9 (0.42) | — | |
| SCHEMBL21718531 | 0.67 | — | — | |
| SCHEMBL6631894 | 0.67 | — | — | |
| SCHEMBL16021583 | 0.67 | — | — | |
| SCHEMBL23571871 | 0.67 | — | — | |
| SCHEMBL21479477 | 0.67 | — | — | |
| SCHEMBL254772 | 0.67 | — | — | |
| SCHEMBL2116642 | 0.64 | BRD9 (0.41) | — | |
| SCHEMBL20844012 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| EP-2606727-A1 | Compounds with nematicidal activity | Bayer CropScience AG (DE) | 2013-06-26 | — | — | EP | disclosed |
| EP-2589294-A1 | Compounds with nematicidal activity | Bayer CropScience AG (DE) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012031090-A2 | SMALL MOLECULE INHIBITORS OF EBOLA AND LASSA FEVER VIRUSES AND METHODS OF USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-03-08 | — | — | WO | disclosed |