Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25504357 | 0.86 | DDB1 (0.63) | DDB1CRBNGPR119HPGDRECQL | |
| SCHEMBL25191738 | 0.86 | DDB1 (0.63) | DDB1CRBNGPR119HPGDRECQL | |
| SCHEMBL30201627 | 0.79 | CRBN (0.70) | DDB1CRBNGPR119MAP4K4CKS1B | |
| SCHEMBL29208509 | 0.79 | CRBN (0.70) | DDB1CRBNGPR119MAP4K4CKS1B | |
| SCHEMBL25074522 | 0.79 | CRBN (0.70) | DDB1CRBNGPR119MAP4K4CKS1B | |
| SCHEMBL24881041 | 0.79 | CRBN (0.70) | DDB1CRBNGPR119MAP4K4CKS1B | |
| SCHEMBL29977355 | 0.79 | CRBN (0.70) | DDB1CRBNGPR119MAP4K4CKS1B | |
| SCHEMBL25193827 | 0.77 | CRBN (0.51) | DDB1CRBNGPR119 | |
| SCHEMBL30441716 | 0.77 | CRBN (0.51) | DDB1CRBNGPR119 | |
| SCHEMBL25504757 | 0.76 | CRBN (0.36) | DDB1CRBNGPR119CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086399-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | NURIX THERAPEUTICS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |