Sugi Predict

Sugi Predict / Compounds / SCHEMBL25504648

SCHEMBL25504648

SCHEMBL25504648

CC(C)[Si]1(C(C)C)OCC2O[C@@H](n3cnc4c(=O)[nH]c(N)nc43)[C@H](O)[C@H]2O[Si](C(C)C)(C(C)C)O1

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 15/20 0.60
▸ PDE3B Q13370 1/20 0.60
▸ PDE3A Q14432 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22983981 1.00 STING1 (0.60) STING1PDE3BPDE3A
SCHEMBL20149811 1.00 STING1 (0.60) STING1PDE3BPDE3A
SCHEMBL20149810 1.00 STING1 (0.60) STING1PDE3BPDE3A
SCHEMBL14946363 1.00 STING1 (0.60) STING1PDE3BPDE3A
SCHEMBL9964274 1.00 STING1 (0.60) STING1PDE3BPDE3A
SCHEMBL9945531 0.91 STING1 (0.49) STING1PDE3BPDE3A
SCHEMBL14946328 0.90 STING1 (0.51) STING1PDE3BPDE3A
SCHEMBL14946312 0.87 STING1 (0.47) STING1PDE3BPDE3A
SCHEMBL26780958 0.87 STING1 (0.47) STING1PDE3BPDE3A
SCHEMBL30527955 0.87 STING1 (0.58) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159922-A1 MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF IONIS PHARMACEUTICALS, INC. (US) 2023-05-25 — — US disclosed