Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25510769 | 0.73 | TSHR (0.43) | DPP4DPP8DPP7 | |
| SCHEMBL22293315 | 0.73 | DPP4 (0.38) | DPP4DPP8DPP7 | |
| SCHEMBL25505408 | 0.73 | DPP4 (0.50) | DPP4 | |
| SCHEMBL26251347 | 0.71 | ATM (0.47) | DPP4DPP8 | |
| SCHEMBL18611612 | 0.69 | DPP4 (0.39) | DPP4DPP8DPP7 | |
| SCHEMBL22402907 | 0.68 | ATM (0.61) | DPP4DPP8 | |
| SCHEMBL24440501 | 0.68 | DPP4 (0.32) | DPP4 | |
| SCHEMBL9944474 | 0.68 | DPP4 (0.37) | DPP4DPP8 | |
| SCHEMBL25498498 | 0.67 | MEN1 (0.33) | DPP4 | |
| SCHEMBL22796893 | 0.67 | ATM (0.42) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144051-A1 | QUINOLINE COMPOUNDS AS INHIBITORS OF KRAS | INCYTE CORPORATION | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230144051-A1 | QUINOLINE COMPOUNDS AS INHIBITORS OF KRAS | KRAS, NRAS, HRAS | DPP4 3819/4885DPP8 3103/4885DPP7 2443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.