Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25190083 | 0.93 | NPC1 (0.44) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL25189566 | 0.92 | MEN1 (0.42) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL31018426 | 0.85 | MEN1 (0.41) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL31018420 | 0.82 | HDAC3 (0.39) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL2188685 | 0.80 | NPC1 (0.57) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL30449430 | 0.80 | CCNE1 (0.37) | ALDH1A1KDM4EMAPTMAPK1NPC1 | |
| SCHEMBL25188638 | 0.80 | CCNE1 (0.37) | ALDH1A1KDM4EMAPTMAPK1NPC1 | |
| SCHEMBL2189559 | 0.80 | ABCB1 (0.48) | HDAC3HDAC1HDAC2HDAC8ALDH1A1 | |
| SCHEMBL25196097 | 0.78 | KDM4E (0.39) | ALDH1A1KDM4EMAPTMAPK1NPSR1 | |
| SCHEMBL25193201 | 0.77 | KDM4E (0.39) | HDAC3HDAC1HDAC2HDAC8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083998-A1 | DIHYDROPYRROLO[3,4C]-PYRAZOLE DERIVATIVES AND THEIR USE IN DIAGNOSIS | AC IMMUNE SA (CH) | 2023-05-19 | — | — | WO | disclosed |