Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.32 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25512171 | 1.00 | CHRNA7 (0.43) | CHRNA7IMPDH2MAPTALDH1A1NPC1 | |
| SCHEMBL25515150 | 1.00 | CHRNA7 (0.43) | CHRNA7IMPDH2MAPTALDH1A1NPC1 | |
| SCHEMBL14669997 | 0.87 | CHRNA7 (0.45) | CHRNA7IMPDH2MAPTALDH1A1NPC1 | |
| SCHEMBL25515287 | 0.86 | CHRNA7 (0.44) | CHRNA7IMPDH2MAPTALDH1A1NPC1 | |
| SCHEMBL25509367 | 0.83 | CHRNA7 (0.45) | CHRNA7IMPDH2MAPTALDH1A1NPC1 | |
| SCHEMBL25509366 | 0.83 | CHRNA7 (0.45) | CHRNA7IMPDH2MAPTALDH1A1NPC1 | |
| SCHEMBL25509368 | 0.83 | CHRNA7 (0.45) | CHRNA7IMPDH2MAPTALDH1A1NPC1 | |
| SCHEMBL25516553 | 0.79 | CHRNA7 (0.42) | CHRNA7IMPDH2MAPTALDH1A1NPC1 | |
| SCHEMBL12647211 | 0.78 | CHRNA7 (0.48) | CHRNA7IMPDH2MAPTALDH1A1NPC1 | |
| SCHEMBL1421391 | 0.78 | CHRNA7 (0.48) | CHRNA7IMPDH2MAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081306-A1 | INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT | TACTOGEN INC (US) | 2023-05-11 | — | — | WO | disclosed |